Long read club

Long read club logo

Really very long reads indeed

Long Read Club

Long read club is part of a recently funded Wellcome Trust Technology Development Award. Our overall goal is to help the genomics community achieve finished quality, complete reference quality genomes routinely and at scale.

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YouTube Channel

Our YouTube channel is at:


Episode 1: What is Long Read Club?

Episode 2: DNA extraction with Jill Herschleb, 10X Genomics

Episode 3: Whole human genome assemblies with Adam Phillippy, NHGRI

Episode 4: The Flye assembler with Mikhail Kolmogorov and Jeffrey Yuan, UCSD

Episode 5: Introducing MorphoSeq: high accuracy long reads from short read platforms, Aaron Darling, Longas Technologies


Head over to our Protocols.io group at:



This page contains links to examplar or notable long-read datasets:

Nanopore NA12878 Consortium

The nanopore human WGS consortium are curating a regularly-updated NA12878 human cell line data release from nanopore data. More information on their Github:


Telomere-to-telomere Consortium

Telomere to telomere consortium logo

At AGBT 2019, the T2T consortium released an extensive dataset for the haploid human CHM13 cell line including 50X ultra-long nanopore coverage, 10X Genomics data, BioNano data. This is complimented by existing PacBio data. The goal of the consortium is to complete a telomere-to-telomere contiguous finished assembly of a haploid human genome.

Find out more at their website: https://sites.google.com/ucsc.edu/t2tworkinggroup/home Data release available via GitHub: https://github.com/nanopore-wgs-consortium/CHM13

E. coli ultra-long read dataset

As part of protocol development, we have generated extensive ultra-long read data for E. coli K-12 MG1655 which is released here in case it is useful for development (e.g. of assembly software).